Conditions We Treat at Texas Ketamine & Wellness Center (Houston)

At Texas Ketamine & Wellness Center, we provide physician-led ketamine therapy in Houston for carefully selected patients with mental health and chronic pain conditions that have not improved with conventional treatment. Many individuals who contact our clinic have already tried combinations of medication management, psychotherapy, and lifestyle changes, yet continue to experience symptoms that limit their quality of life.

This page is your starting point. It’s designed as a central hub so you can quickly find your condition and explore dedicated pages for more detail. If you’re unsure which condition best matches what you’re experiencing, our team can guide you during a confidential consultation.

Common reasons patients consider ketamine therapy include:

Important: Ketamine therapy is not appropriate for everyone. We prioritize medical screening, informed consent, and safe monitoring for every patient.

What Makes Ketamine Therapy Different?

Traditional antidepressants and anti-anxiety medications generally work through serotonin and norepinephrine pathways and may take weeks to provide noticeable benefit. Ketamine works through a different set of mechanisms, primarily involving NMDA receptor modulation and glutamate pathways, which are closely linked to neuroplasticity (the brain’s ability to form and revise connections).

In clinical practice, some patients report that ketamine helps reduce symptom intensity, emotional rigidity, and overwhelm—particularly when standard treatments have plateaued. However, response varies, and our clinic focuses on careful selection and realistic expectations.

Our approach is:

  • Physician-led and safety-first

  • Medical Safety and Clinical Protocols

  • Structured and monitored (vital signs and recovery observation)

  • Individualized to your history, goals, and response over time

  • Designed to complement—not replace—ongoing care when appropriate

Mental Health Conditions Treated

Treatment-Resistant Depression (TRD)

Depression can show up as more than sadness. Many patients experience emotional numbness, fatigue, reduced motivation, sleep disruption, irritability, or difficulty concentrating. When depression persists despite appropriate trials of antidepressants and therapy, it may be considered treatment-resistant depression.

Patients commonly explore ketamine therapy for depression when they’ve had:

  • Multiple medication trials with incomplete relief

  • Side effects limiting medication use

  • Ongoing symptoms despite therapy

  • Depression that disrupts work, relationships, or self-care

Goal of care: symptom reduction and improved function—while maintaining realistic expectations and ongoing reassessment.

➡️ Ketamine Therapy for Depression in Houston

Anxiety Disorders (including GAD, Panic, Social Anxiety)

Anxiety disorders can involve persistent worry, racing thoughts, physical tension, insomnia, irritability, or panic attacks. For many patients, anxiety is chronic—not situational—and may remain disruptive despite standard treatments.

We commonly evaluate:

  • Generalized Anxiety Disorder (GAD)

  • Panic disorder

  • Social anxiety

  • Anxiety co-occurring with depression or PTSD

Ketamine therapy may be considered for moderate-to-severe anxiety, particularly when traditional approaches have not been sufficient. Some patients report a calmer baseline and reduced reactivity after treatment.

➡️ Ketamine Therapy for Anxiety in Houston

Post-Traumatic Stress Disorder (PTSD)

PTSD may involve intrusive memories, hypervigilance, avoidance, mood changes, irritability, sleep disruption, or emotional numbing. Trauma-focused therapy remains foundational, yet symptoms can persist despite high-quality care.

Ketamine is being studied as an adjunct for PTSD due to its effects on neural circuits involved in fear response and emotional processing. While not a replacement for trauma therapy, ketamine may help some individuals reduce symptom burden enough to engage more effectively in ongoing treatment.

➡️ Ketamine Therapy for PTSD in Houston

Obsessive-Compulsive Disorder (OCD)

OCD is characterized by intrusive thoughts (obsessions) and repetitive behaviors or mental rituals (compulsions) performed to reduce distress. First-line treatment usually includes ERP therapy and medication.

For treatment-resistant OCD, ketamine has gained interest because OCD is strongly connected to glutamate signaling and specific brain circuit patterns. Response can vary and may be temporary, so we emphasize careful screening and coordination with ongoing therapy.

➡️ Ketamine Therapy for OCD in Houston

Bipolar Depression (Carefully Screened Cases)

Bipolar disorder requires precise diagnosis and careful management. Some individuals with bipolar disorder experience prolonged depressive episodes that are difficult to treat.

Ketamine therapy may be considered for bipolar depression in carefully selected patients, often with coordination involving the patient’s psychiatrist. We screen conservatively to reduce the risk of mood destabilization and ensure appropriate support.

➡️ Ketamine Therapy for Bipolar Depression in Houston

Suicidal Ideation (Non-Emergency Treatment Planning)

Ketamine has been studied for rapid reduction of suicidal ideation in controlled medical settings. However, it is not a substitute for emergency care.

If you are experiencing active suicidal thoughts with intent or plan, call 911 or go to the nearest emergency department.

For select patients with severe symptoms who are stable enough for outpatient evaluation, ketamine therapy may be considered as part of a comprehensive treatment plan and close follow-up.

➡️ Ketamine Therapy for Suicidal Ideation / Rapid Symptom Relief

Chronic Pain Conditions Treated

Chronic pain is not always purely “structural.” In many conditions, the nervous system becomes sensitized, amplifying pain signals. Ketamine has a well-established history of medical use and has been studied for certain pain syndromes, particularly where NMDA receptor activity contributes to pain sensitization.

We commonly evaluate the following:

Complex Regional Pain Syndrome (CRPS)

CRPS can involve severe pain, changes in skin color or temperature, swelling, and functional limitation, often after an injury or surgery. It can be challenging to treat and may significantly impact quality of life.

Ketamine therapy is sometimes considered for CRPS due to NMDA receptor involvement in pain sensitization. We evaluate each case individually to determine appropriateness.

➡️ Ketamine Therapy for CRPS in Houston

Neuropathic Pain

Neuropathic pain may present as burning, tingling, shooting, or electric sensations and can arise from nerve injury or dysfunction. Standard medications can provide partial relief but may not fully address symptoms.

Ketamine may be considered for refractory neuropathic pain in select patients, especially when symptoms significantly affect sleep and function.

➡️ Ketamine Therapy for Neuropathic Pain in Houston

Fibromyalgia and Central Sensitization Syndromes

Fibromyalgia often involves widespread pain, fatigue, sleep disturbance, brain fog, and heightened sensitivity. These symptoms are frequently linked to altered pain processing rather than localized tissue damage.

Ketamine therapy may be considered when conventional strategies have not provided adequate relief, particularly in patients with significant functional impairment.

➡️ Ketamine Therapy for Fibromyalgia in Houston

Chronic Migraine and Refractory Headache Disorders

Some patients with chronic migraine or refractory headache disorders seek additional options when typical preventive and abortive therapies have failed. Ketamine therapy may be explored in select cases as part of a broader, individualized plan.

➡️ Ketamine Therapy for Chronic Migraine in Houston

Cancer-Related Pain and Palliative Support (Select Cases)

Ketamine has been used in palliative care settings for complex or refractory pain. For select patients, ketamine therapy may be discussed as a supportive option when standard pain strategies are not sufficient.

➡️ Ketamine Therapy for Cancer-Related Pain in Houston

Conditions We Evaluate Carefully (and When Ketamine May Not Be Appropriate)

Not every patient is a candidate. We screen carefully for medical and psychiatric contraindications, including but not limited to:

  • Uncontrolled hypertension or certain cardiovascular conditions

  • Specific psychiatric diagnoses requiring specialized management

  • Active substance use disorder concerns

  • Medication interactions or safety considerations

If ketamine therapy is not appropriate, we will explain why and discuss alternative paths forward.

Our Commitment to Physician-Led Safety

Patients choose Texas Ketamine & Wellness Center because we emphasize:

  • Physician-led evaluation and oversight

  • Conservative treatment planning

  • Vital-sign monitoring and structured recovery observation

  • Clear education and informed consent

  • Coordination with your outside providers when appropriate

Our goal is to provide an environment where patients feel respected, informed, and supported.

Ready to Take the Next Step?

If you are exploring ketamine therapy for depression, anxiety, PTSD, OCD, bipolar depression, or chronic pain, we invite you to schedule a confidential consultation. We’ll review your history and help you determine whether ketamine therapy may be appropriate for your goals.

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